On March 12, 2021, US Customs and Border Protection (CBP) published in the Federal Register a final rule [CBP Dec. 21-05] that amends the CBP regulations to reflect an extension of import restrictions on certain archaeological and ecclesiastical ethnological material [Pre-Columbian archaeological material ranging approximately from 1500 B.C. to 1530 A.D. and ecclesiastical ethnological material of the Colonial period ranging approximately from A.D. 1530 to 1830] from Colombia. The restrictions, which were originally imposed by CBP Dec. 06-09 and last extended by CBP Dec. 16-05, are due to expire on March 15, 2021. The Assistant Secretary for Educational and Cultural Affairs, US Department of State, has made the requisite determinations for extending the import restrictions that previously existed, and the Governments of the United States and Colombia entered into a new agreement to reflect the extension of these import restrictions. The new agreement, which entered into force on March 10, 2021, supersedes the existing Memorandum of Understanding (MOU) that became effective on March 15, 2006, and enabled the promulgation of the existing import restrictions. Accordingly, the import restrictions will remain in effect for an additional five years, and the CBP regulations are being amended to reflect this further extension until March 10, 2026. CBP Dec. 06-09 contains the amended Designated List of archaeological and ecclesiastical ethnological material from Colombia to which the restrictions apply. The final rule was effective on March 10, 2021.